Yang Xu, Xiang Nan, Wei Bin
Postgraduate student, Department of Prosthodontics, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Department of Prosthodontics, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China.
Postgraduate student, Department of Prosthodontics, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Department of Prosthodontics, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
J Prosthet Dent. 2014 Nov;112(5):1212-6. doi: 10.1016/j.prosdent.2013.12.022. Epub 2014 May 17.
Selective laser melting (SLM) alloy is gaining popularity in prosthetic dentistry. However, its biocompatibility has been of some concern because of long-term exposure to fluoride in the oral environment.
The purpose of this study was to examine the effect of fluoride concentration on ion release from Co-Cr-Mo alloy specimens fabricated using either SLM or lost-wax casting when immersed in an artificial saliva solution containing fluoride.
Specimens were prepared with either a SLM system for the SLM alloy or conventional lost-wax techniques for the cast alloy. The specimen surfaces were wet ground with silicon carbide paper (400, 800, and 1200 grit) and immersed in modified artificial saliva solutions, the pH of which had been adjusted to 5.0 with lactic acid and which contained NaF at concentrations of 0.00%, 0.05%, 0.1%, or 0.2%. The metal ion content of the solution was determined with an inductively coupled plasma mass spectrometer. The results were submitted to 2-way ANOVA and regression analysis (α=.05).
Fluoride concentration significantly influenced the elemental ion release from both the SLM and cast alloys. The quantity of ions released increased significantly with increasing fluoride concentration. The ion release from the cast specimens was significantly greater than that from the SLM specimens.
The performance of the SLM alloy in immersion tests demonstrates that this new technique is a superior choice because of its good biocompatibility.
选择性激光熔化（SLM）合金在口腔修复领域越来越受欢迎。然而，由于长期暴露于口腔环境中的氟化物，其生物相容性一直受到一些关注。
本研究的目的是研究氟化物浓度对使用SLM或失蜡铸造法制造的Co-Cr-Mo合金试样在浸入含氟人工唾液溶液时离子释放的影响。
使用SLM系统制备SLM合金试样，使用传统失蜡技术制备铸造合金试样。试样表面用碳化硅砂纸（400、800和1200目）湿磨，然后浸入用乳酸将pH值调节至5.0且含有浓度为0.00%、0.05%、0.1%或0.2%的NaF的改良人工唾液溶液中。用感应耦合等离子体质谱仪测定溶液中的金属离子含量。结果进行双向方差分析和回归分析（α=0.05）。
氟化物浓度显著影响SLM合金和铸造合金的元素离子释放。随着氟化物浓度的增加，释放的离子量显著增加。铸造试样的离子释放量明显大于SLM试样。
SLM合金在浸泡试验中的表现表明，由于其良好的生物相容性，这种新技术是一个更好的选择。
