Haane C, Colombo-Benkmann M
Klinik für Allgemein-und Viszeralchirurgie, Universitätsklinikum Münster, Albert Campus 1, 48149, Münster, Deutschland,
Chirurg. 2014 Jun;85(6):481-6. doi: 10.1007/s00104-013-2667-9.
The early detection of recurrent thyroid cancer and focussed surgery are essential for patients' prognosis. Using I-131 whole body scintigraphy is often not sufficient to detect recurrent carcinoma making other imaging methods necessary to identify the tumor. Recent studies showed that positron emission tomography-computed tomography (PET/CT) is able to identify recurrent carcinoma and metastasis at an early stage.
The aim of this study was an evaluation of the impact of PET/CT on diagnostic and operation strategies in recurrent thyroid cancer.
A review of the literature was carried out combined with a case report from the daily practice. Furthermore, flow charts were created to clarify the aftercare procedure.
In patients with recurrent thyroid cancer PET/CT significantly increased the identification of recurrent tumors and metastases. Depending on the subtype of cancer, different tracers are used. The use of a metabolically active tracer which shows the increase of tumor metabolism and the morphological correlation of the tumor using a CT scan enable preoperative planning for a focussed surgical approach.
The PET/CT procedure should be an integral part of the aftercare procedure in thyroid cancer for early identification of recurrent tumors and to enable focussed surgery.
复发性甲状腺癌的早期检测和精准手术对患者预后至关重要。使用I-131全身闪烁扫描通常不足以检测复发性癌，因此需要其他成像方法来识别肿瘤。最近的研究表明，正电子发射断层扫描-计算机断层扫描（PET/CT）能够在早期识别复发性癌和转移灶。
本研究的目的是评估PET/CT对复发性甲状腺癌诊断和手术策略的影响。
结合日常实践中的病例报告进行文献综述。此外，还绘制了流程图以阐明后续治疗程序。
在复发性甲状腺癌患者中，PET/CT显著提高了复发性肿瘤和转移灶的识别率。根据癌症的亚型，使用不同的示踪剂。使用代谢活性示踪剂显示肿瘤代谢增加，并通过CT扫描显示肿瘤的形态相关性，从而能够进行精准手术的术前规划。
PET/CT程序应成为甲状腺癌后续治疗程序的一个组成部分，以便早期识别复发性肿瘤并进行精准手术。
