抗小鼠磨牙乳头细胞单克隆抗体的制备。
Production of monoclonal antibodies against mouse molar papilla cells.
作者信息
Zidan G, Ruch J V
机构信息
Institut de Biologie Médicale, Faculté de Médecine, Université Louis Pasteur, Strasbourg, France.
出版信息
Int J Dev Biol. 1989 Jun;33(2):245-59.
PMID:2484286
Abstract
To develop markers for the analysis of the molecular mechanisms of dental papilla cells differentiation, 10 monoclonal antibodies were produced against trypsin-isolated mouse molar dental papilla cells. These antibodies identify matrix components, cell membrane associated antigens and intracellular-constituents. Changes of the staining patterns were correlated with a typological hierarchy of dental papilla cells and with terminal differentiation of odontoblasts.
摘要
为了开发用于分析牙乳头细胞分化分子机制的标志物，制备了10种针对胰蛋白酶分离的小鼠磨牙牙乳头细胞的单克隆抗体。这些抗体可识别基质成分、细胞膜相关抗原和细胞内成分。染色模式的变化与牙乳头细胞的类型层次以及成牙本质细胞的终末分化相关。
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