Medical University of South Carolina, Charleston, SC, USA.
Transfus Med Hemother. 2014 Apr;41(2):153-5. doi: 10.1159/000357985. Epub 2014 Mar 5.
Passenger lymphocyte syndrome (PLS) is most often a result of an ABO minor mismatch between stem cell or solid organ donor and recipient. Relatively few cases of PLS have been reported resulting from non-ABO red cell antibodies.
A blood group O/Rh-positive patient received a stem cell transplant from an A/Rh-negative donor who had an identifiable anti-D. Even though the plasma of the stem cell product was reduced and replaced with an electrolyte solution, the recipient developed a positive antibody screen, positive direct antiglobulin test, and significant hemolysis 8 days after transplantation.
PLS can result from non-ABO antibodies and can be associated with a significant degree of hemolysis.
乘客淋巴细胞综合征（PLS）通常是干细胞或实体器官供体和受者之间 ABO 次要不相容的结果。由于非 ABO 红细胞抗体导致 PLS 的病例相对较少。
一名血型为 O/Rh 阳性的患者接受了来自 A/Rh 阴性供体的干细胞移植，该供体具有可识别的抗-D。尽管干细胞制品的血浆被减少并用电解质溶液替代，但受者在移植后 8 天出现了阳性抗体筛查、阳性直接抗球蛋白试验和明显的溶血。
PLS 可由非 ABO 抗体引起，并可伴有明显程度的溶血。
