Henares García P
Semergen. 2012 Jan-Feb;38(1):53-5.
Rhabdomyolysis is a syndrome characterised by the destruction of the skeletal muscle, releasing myoglobin, electrolytes and muscle enzymes into the circulatory system. The causes are varied, the most frequent being intense physical exercise, trauma and alcohol. The clinical presentation is also variable and the classic symptoms of muscular pain, weakness and dark urine are not always present. The diagnosis is usually made after detecting an increase in serum levels of the enzyme creatine phosphokinase (CPK) higher or equal to five times the upper limit of normal. The most important aspect of the treatment is the early and aggressive hydration of the patient with intravenous normal saline infusion which avoids complications such as acute renal failure. The prognosis is always excellent when the treatment is carried out early.
横纹肌溶解症是一种以骨骼肌破坏为特征的综合征，会将肌红蛋白、电解质和肌肉酶释放到循环系统中。其病因多种多样，最常见的是剧烈体育锻炼、创伤和酒精。临床表现也各不相同，肌肉疼痛、无力和深色尿液等典型症状并不总是出现。通常在检测到血清肌酸磷酸激酶（CPK）水平升高至正常上限的五倍或更高时做出诊断。治疗的最重要方面是通过静脉输注生理盐水对患者进行早期积极补液，这可避免诸如急性肾衰竭等并发症。如果早期进行治疗，预后总是很好。
