Servicio de Medicina Interna, Hospital San Pedro, Logroño, España.
Med Clin (Barc). 2022 Mar 25;158(6):277-283. doi: 10.1016/j.medcli.2021.09.025. Epub 2021 Dec 3.
Rhabdomyolysis is characterized by the release of intracellular elements after the destruction of skeletal muscle. Is characterized by the presence of muscle pain, weakness, and dark urine, associated with elevated creatine kinase (CK). The causes related to this syndrome are varied, being traumatic etiology, immobilization, sepsis, drugs and alcohol the most frequent. CK values are used for diagnosis and prognosis, being renal dysfunction the most serious complication. Treatment is based on early and intensive fluid therapy to avoid kidney complications.
横纹肌溶解症的特征是骨骼肌破坏后细胞内成分的释放。其特征是肌肉疼痛、无力和深色尿,并伴有肌酸激酶(CK)升高。与该综合征相关的原因多种多样,最常见的是创伤性病因、固定、败血症、药物和酒精。CK 值用于诊断和预后,肾功能障碍是最严重的并发症。治疗基于早期和强化的液体疗法,以避免肾脏并发症。