Crellin A M, Marks A, Maher E J
Mount Vernon Hospital, Regional Centre for Radiotherapy and Oncology, Northwood, Middlesex, U.K.
Clin Oncol (R Coll Radiol). 1989 Nov;1(2):63-6. doi: 10.1016/s0936-6555(89)80036-6.
A sample of 42 out of 80 delegates at RADIOLOGY '87 were asked about their treatment of a hypothetical patient with bone metastases from carcinoma of the breast. Details of their experience, the proportion of palliative work performed and the location of their centre were obtained. Only 36% gave a single fraction of radiotherapy, whereas 64% used multiple fractions. This confirms that despite many publications suggesting single fractions of radiotherapy are more cost effective and as good as fractionated treatment schedules in terms of pain relief, the need for retreatment and side-effects, the majority of British radiotherapists still use multiple fractions. Of the group using multiple fractions, 67% gave training as a reason for not using a single fraction, departmental policy being the second most quoted reason. Fear of recurrence, problems of retreatment and acute nausea were more of an influence than initial response or long-term effects. The presence of neurological signs or symptoms made the majority of delegates choose multiple fractions. An increased use of single fractions was noted in the Midlands and North of England compared with the South. Practice is unlikely to change unless there is an increased emphasis on palliative techniques in training.
在“1987年放射学大会”的80名代表中,抽取了42名作为样本,询问他们对一名假设的乳腺癌骨转移患者的治疗方法。获取了他们的经验细节、姑息治疗工作的比例以及他们所在中心的位置。只有36%的人采用单次放疗,而64%的人采用多次放疗。这证实了尽管有许多出版物表明,单次放疗在成本效益方面更高,并且在缓解疼痛、再治疗需求和副作用方面与分次治疗方案一样好,但大多数英国放射治疗师仍然采用多次放疗。在采用多次放疗的人群中,67%的人将培训作为不采用单次放疗的原因,部门政策是第二大常被提及的原因。对复发的恐惧、再治疗问题和急性恶心比初始反应或长期影响的影响更大。神经系统体征或症状的出现使大多数代表选择多次放疗。与南部相比,英格兰中部和北部单次放疗的使用有所增加。除非在培训中更加重视姑息治疗技术,否则这种做法不太可能改变。