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复发性免疫性流产治疗管理的新视角。

New perspectives for the therapeutic management of recurrent immunological abortion.

作者信息

Perino A, Barba G, Cimino C, Costa P, Pignatone C, Scaglione G, Zangara C, Cittadini E, Marcenò R, Cavallaro A M

机构信息

Clinica Ostetrica e Ginecologica (R), Università di Palermo.

出版信息

Acta Eur Fertil. 1989 Nov-Dec;20(6):359-62.

PMID:2484960
Abstract

Up to now the only effective therapy for recurrent abortion syndrome due to the absence of the so-called blocking-factor has been active immunotherapy with partner or third-party donor mononucleates. The Authors report their in vivo and in vitro experience with high-dose intravenous gammaglobulin (i IV Ig) in order to treat women with recurrent abortion syndrome. In the Authors opinion there are sufficient experimental reasons for continuing this research with IV Ig obtained from multiparous women plasma pools.

摘要

到目前为止,对于因缺乏所谓的封闭因子而导致的复发性流产综合征,唯一有效的治疗方法是用配偶或第三方供体的单核细胞进行主动免疫治疗。作者报告了他们使用大剂量静脉注射丙种球蛋白(i-IV Ig)治疗复发性流产综合征女性的体内和体外实验经验。作者认为,有充分的实验依据继续开展从经产妇血浆库中获取的静脉注射丙种球蛋白的研究。

相似文献

1
New perspectives for the therapeutic management of recurrent immunological abortion.复发性免疫性流产治疗管理的新视角。
Acta Eur Fertil. 1989 Nov-Dec;20(6):359-62.
2
The use of three different therapeutic protocols according to the immunologic pathology present in three women with recurrent spontaneous abortion and fetal death for immunologic reasons: flucortolone and salicylates; high-dose intravenous gammaglobulins; subcutaneous heparin.针对三名因免疫原因反复自然流产和胎儿死亡的女性,根据其免疫病理学情况使用了三种不同的治疗方案:氟可的索和水杨酸盐;大剂量静脉注射丙种球蛋白;皮下注射肝素。
Acta Eur Fertil. 1990 Jul-Aug;21(4):177-83.
3
Immunological problems in the recurrent abortion syndrome.
Acta Eur Fertil. 1989 Jul-Aug;20(4):199-202.
4
The results of investigations for blocking antibody and autoantibodies help to choose between different immunological treatments for recurrent abortion.封闭抗体和自身抗体的检测结果有助于在复发性流产的不同免疫治疗方法之间做出选择。
Acta Eur Fertil. 1989 Jul-Aug;20(4):193-8.
5
Immunologic recurrent abortion: comparison between immunotherapies.免疫性复发性流产:免疫疗法之间的比较
Acta Eur Fertil. 1991 May-Jun;22(3):171-5.
6
[Immunotherapy of recurrent spontaneous miscarriages (idiopathic abortive disease): preliminary results].[复发性自然流产(特发性流产疾病)的免疫疗法:初步结果]
Rev Med Brux. 1992 Apr;13(4):107-12.
7
Induction of MLR-Bf and protection of fetal loss: a current double blind randomized trial of paternal lymphocyte immunization for women with recurrent spontaneous abortion.混合淋巴细胞反应阻断因子的诱导与胎儿丢失的预防:一项针对复发性自然流产女性的父方淋巴细胞免疫的双盲随机试验。
Int Immunopharmacol. 2004 Feb;4(2):289-98. doi: 10.1016/j.intimp.2004.01.001.
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[Comparative study of the third party and paternal leukocyte immunization in recurrent spontaneous abortion of lowered maternal-fetal immuno-recognition].[母胎免疫识别降低所致复发性自然流产中第三方与父方白细胞免疫的比较研究]
Zhonghua Fu Chan Ke Za Zhi. 1998 Oct;33(10):597-600.
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[The immunologically-caused early abortion].[免疫性早期流产]
Z Geburtshilfe Perinatol. 1989 Nov-Dec;193(6):247-50.
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Female third party lymphocytes are effective for immunotherapy of patients with unexplained primary recurrent spontaneous abortion: A retrospective analysis of outcomes.女性第三方淋巴细胞对不明原因原发性复发性自然流产患者的免疫治疗有效:结局的回顾性分析
Eur J Contracept Reprod Health Care. 2015;20(6):428-37. doi: 10.3109/13625187.2015.1046593. Epub 2015 May 19.