Cao Hai-Xia, Zhu Ke-Xiang, Fan Jian-Gao, Qiao Liang
Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of medicine, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai 200092, China.
Anticancer Agents Med Chem. 2014;14(6):793-9. doi: 10.2174/1871520614666140521120811.
Garlic (Allium sativam L.) is widely used in traditional herbal remedies and alternative medicine. The potential health benefits of garlic are largely attributed to its metabolic byproducts. Extensive in vivo and in vitro studies has demonstrated that the garlic derivatives possess anti-cancer effects, but the underlying mechanisms are not completely understood. In this mini-review, we aim to summarize the reported biological effects of garlic products as anti-tumor agents, and present the possible molecular mechanisms responsible for the anti-carcinogenesis effects of garlic and its derivatives.
大蒜（Allium sativam L.）广泛应用于传统草药疗法和替代医学中。大蒜对健康的潜在益处主要归因于其代谢副产物。大量的体内和体外研究表明，大蒜衍生物具有抗癌作用，但其潜在机制尚未完全明确。在本综述中，我们旨在总结已报道的大蒜产品作为抗肿瘤剂的生物学效应，并阐述大蒜及其衍生物抗癌作用可能的分子机制。
