He Haiqing, Fan Shufeng, Li Yujing, Ke Mang, Li Yangfei, Chen Bangwen, Yu Hongyuan
Department of Radiology, Taizhou Hospital, Linhai 317000, China.
Department of Urinary Surgery, Taizhou Hospital, Linhai 317000, China. Email:
Zhonghua Yi Xue Za Zhi. 2014 Apr 15;94(14):1051-4.
To explore the magnetic resonance imaging (MRI) manifestations of early prostatic carcinoma (PCa) in central zone (CZ) .
A total of 284 cases of PCa were scanned by MRI while 24 cases of carcinoma in 28 PCa focus were in central zone. Their T1WI, T2WI, DWI and ADC value characteristics were analyzed respectively and the completeness of annular low signal between central and peripheral zones were observed. At the same time, 45 cases of PCa were located in peripheral zone (PZ) . Twenty cases of benign prostatic hyperplasia (BPH) were comparatively analyzed. All cases received a histological diagnosis.
Most cases of early PCa in CZ demonstrated ill-defined margin, amorphous shape and equal signal intensity on T1WI, low signal intensity on T2WI and high signal intensity on DWI. The mean ADC value for PCa focus was (0.867 ± 0.074)×10(-3) mm(2)/s and PCa foci were enhanced slightly. In these cases, most annular low signals between CZ and PZ were destroyed. The difference of ADC values between PCa in CZ and PZ groups ((0.914 ± 0.066) ×10(-3) mm(2)/s ) had no statistic significance (P > 0.05) , but the ADC values between PCa and BPH in CZ groups ((1.517 ± 0.315) ×10(-3) mm(2)/s ) had statistically significant difference (P < 0.05).
Some reliable diagnostic characteristics on MRI may be used for an early diagnosis of PCa in CZ.
探讨前列腺中央带早期前列腺癌的磁共振成像（MRI）表现。
对284例前列腺癌患者行MRI检查，其中28个前列腺癌病灶中的24例癌灶位于中央带，分别分析其T1WI、T2WI、DWI及ADC值特征，并观察中央带与外周带之间环形低信号的完整性。同时，45例前列腺癌位于外周带，并对20例良性前列腺增生患者进行对比分析。所有病例均获得组织学诊断。
中央带早期前列腺癌多数表现为边界不清、形态不规则，T1WI呈等信号，T2WI呈低信号，DWI呈高信号。前列腺癌灶平均ADC值为（0.867±0.074）×10⁻³mm²/s，癌灶呈轻度强化。此类病例中，多数中央带与外周带之间的环形低信号被破坏。中央带前列腺癌组与外周带前列腺癌组ADC值[（0.914±0.066）×10⁻³mm²/s]差异无统计学意义（P＞0.05），但中央带前列腺癌组与良性前列腺增生组ADC值[（1.517±0.315）×10⁻³mm²/s]差异有统计学意义（P＜0.05）。
MRI上一些可靠的诊断特征可用于前列腺中央带前列腺癌的早期诊断。
