Mouat Emily E, Davis Garrett J, Drobatz Kenneth J, Wallace Koranda A
Surgery Department, Red Bank Veterinary Hospital, Tinton Falls, NJ (E.M., G.D.); and Section of Critical Care, Department of Clinical Studies (K.D.) and Laboratory of Pathology and Toxicology (K.W.), Matthew J. Ryan Teaching Hospital, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA.
J Am Anim Hosp Assoc. 2014 Jul-Aug;50(4):254-63. doi: 10.5326/JAAHA-MS-6111.
The objectives of this study were to evaluate blood and abdominal fluid lactate and glucose, fluid cytology, culture, and volume 24 and 48 hr following intestinal resection and anastomosis in dogs with and without closed-suction drains and to correlate findings with survival. Thirty-five client-owned dogs that underwent intestinal resection and anastomosis were prospectively enrolled in the study. Abdominal fluid was submitted for culture at surgery and again 24 hr postoperatively. Twenty-four and 48 hr postoperatively, blood and abdominal fluid glucose and lactate were measured and fluid was submitted for cytology. Abdominal fluid was collected either from a closed-suction drain or by abdominocentesis. Patients were followed either for 14 days or until death. Comparisons were made based on development of dehiscence and presence or absence of a drain. Patients with dehiscence were more likely to have positive cultures at 24 hr and to have had more bowel resected. Surviving patients without drains had significantly smaller differences in blood and fluid glucose and lactate both 24 and 48 hr postoperatively than surviving patients with drains. The significant differences identified between patients with and without drains suggests a need for further research into the effect of drains on abdominal fluid values.
本研究的目的是评估在有或没有闭式引流的情况下,犬进行肠切除吻合术后24小时和48小时的血液及腹腔液乳酸和葡萄糖水平、液体细胞学、培养情况及液体量,并将结果与生存率相关联。35只接受肠切除吻合术的客户-owned犬被前瞻性纳入本研究。手术时及术后24小时采集腹腔液进行培养。术后24小时和48小时,测量血液及腹腔液葡萄糖和乳酸水平,并采集液体进行细胞学检查。腹腔液通过闭式引流或腹腔穿刺收集。对患者随访14天或直至死亡。根据吻合口裂开情况及是否有引流进行比较。发生吻合口裂开的患者在术后24小时培养结果更可能为阳性,且切除的肠段更多。没有引流的存活患者在术后24小时和48小时血液及液体葡萄糖和乳酸水平的差异显著小于有引流的存活患者。有引流和没有引流的患者之间发现的显著差异表明需要进一步研究引流对腹腔液值的影响。 (注:“client-owned”这里表述不太准确,推测可能是“客户拥有的”之类意思,但不影响整体理解,按照字面翻译了)