Department of Urology, University of South Florida and Department of Genitourinary Oncology, Moffitt Cancer Center, Tampa, Fl, USA.
Int Braz J Urol. 2014 Mar-Apr;40(2):225-31. doi: 10.1590/S1677-5538.IBJU.2014.02.13.
The limitations of traditional ureteral stents in patients with deficiencies in ureteral drainage have resulted in frequent stent exchanges. The implementation of metallic stents was introduced to improve the patency rates of patients with chronic upper urinary tract obstruction, obviating the need for frequent stent exchanges. We report our clinical experiences with the use of metallic ureteral stents in the management of poor ureteral drainage.
Fifty patients underwent metallic ureteral stent placement from 2009 to 2012. Stent failure was defined as an unplanned stent exchange, need for nephrostomy tube placement, increasing hydronephrosis with stent in place, or an elevation in serum creatinine. Stent life was analyzed using the Kaplan-Meier methodology, as this was a time dependent continuous variable. A cost analysis was similarly conducted.
A total of 97 metallic stents were placed among our cohort of patients: 63 in cases of malignant obstruction, 33 in the setting of cutaneous ureterostomies, and 1 in an ileal conduit urinary diversion. Overall, stent failure occurred in 8.2% of the stents placed. Median stent life was 288.4 days (95% CI: 277.4-321.2 days). The estimated annual cost for traditional polymer stents (exchanged every 90 days) was $9,648-$13,128, while the estimated cost for metallic stents was $4,211-$5,313.
Our results indicate that metallic ureteral stent placement is a technically feasible procedure with minimal complications and is well tolerated among patients. Metallic stents can be left in situ for longer durations and provide a significant financial benefit when compared to traditional polymer stents.
传统输尿管支架在存在输尿管引流缺陷的患者中存在局限性,导致频繁更换支架。金属支架的应用旨在提高慢性上尿路梗阻患者的通畅率,避免频繁更换支架。我们报告了在管理输尿管引流不良患者中使用金属输尿管支架的临床经验。
2009 年至 2012 年期间,50 例患者接受了金属输尿管支架置入术。支架失败定义为计划外更换支架、需要放置肾造口管、支架在位时肾积水加重或血清肌酐升高。使用 Kaplan-Meier 方法分析支架的生存时间,因为这是一个时间相关的连续变量。同时进行了成本分析。
在我们的患者队列中,共放置了 97 根金属支架:63 例恶性梗阻,33 例皮肤输尿管造口术,1 例回肠导管尿流改道术。总体而言,8.2%的支架发生了支架失败。中位支架生存时间为 288.4 天(95%CI:277.4-321.2 天)。传统聚合物支架(每 90 天更换一次)的估计年度费用为 9648-13128 美元,而金属支架的估计费用为 4211-5313 美元。
我们的结果表明,金属输尿管支架置入术是一种技术可行的操作,并发症少,患者耐受性良好。与传统聚合物支架相比,金属支架可以更长时间地留在原位,并具有显著的经济效益。