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多中心应用金属输尿管支架治疗恶性和慢性良性输尿管梗阻的经验。

Multicenter experience with metallic ureteral stents for malignant and chronic benign ureteral obstruction.

机构信息

Department of Urology, The Ohio State University Medical Center, Columbus, Ohio, USA.

出版信息

J Endourol. 2010 Jul;24(7):1189-93. doi: 10.1089/end.2010.0121.

Abstract

BACKGROUND AND PURPOSE

A new coil-based metallic ureteral stent offers greater radial strength with longer indwelling time compared with plastic stents. This multicenter retrospective study reviews the clinical experience with this stent for malignant or benign chronic ureteral obstruction.

PATIENTS AND METHODS

Patients had stent placement in a retrograde fashion. We analyzed preplacement and postplacement renal imaging to determine degree of hydronephrosis. Stent encrustation was determined by either visual inspection at the time of stent change or plain abdominal radiography. Preoperative and follow-up serum creatinine values were compared for each patient.

RESULTS

A total of 76 stents in 59 renal units (40 patients) were successfully placed. Creatinine value follow-up on 54 renal units showed 20 (37%) units to have stable, 15 (28%) improved, and 19 (35%) with worsening values. No stent showed encrustation on plain radiography despite it being seen on two during direct visualization. Three stents needed operative removal with either percutaneous nephrolithotomy or cystolitholapaxy. Fifteen of 41 (37%) metallic stents placed because of an obstructed plastic stent also became obstructed. At last follow-up, 6 of 40 patients were kept from nephrostomy tubes because of the metallic stent.

CONCLUSIONS

Metallic stents are a viable alternative to nephrostomy tubes in patients in whom conventional stents fail because of malignant obstruction, but patients need to be followed closely. Stent encrustation that resulted in retained stents was poorly visualized on plain radiography. Patients still remain at risk for obstruction, urinary tract infections, and lower urinary tract symptoms from the metallic stent.

摘要

背景与目的

一种新型的基于线圈的金属输尿管支架在保持更长留置时间的同时提供了更大的径向强度,与塑料支架相比。这项多中心回顾性研究回顾了该支架在恶性或良性慢性输尿管梗阻中的临床应用经验。

患者和方法

患者以逆行方式放置支架。我们分析了放置支架前后的肾脏影像学检查,以确定肾积水的程度。支架结壳通过在更换支架时的目视检查或腹部平片来确定。比较了每位患者的术前和随访血清肌酐值。

结果

共成功放置了 76 个支架,涉及 59 个肾脏单位(40 名患者)。54 个肾脏单位的肌酐值随访显示,20 个(37%)单位稳定,15 个(28%)改善,19 个(35%)恶化。尽管在直接观察时发现有两个支架存在结壳,但平片未见结壳。有 3 个支架需要手术取出,方法为经皮肾镜碎石术或膀胱结石切开术。因塑料支架阻塞而放置的 41 个金属支架中有 15 个也发生了阻塞。最后一次随访时,由于金属支架的存在,40 名患者中有 6 名避免了肾造口管。

结论

在因恶性梗阻而导致常规支架失败的患者中,金属支架是肾造口管的可行替代方案,但需要密切随访。导致支架滞留的支架结壳在平片上显示不佳。患者仍然存在支架阻塞、尿路感染和下尿路症状的风险。

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