Brik R, Shapira D, Lorber M, Nahir M
Pediatrics Dept., Rambam Medical Center, Haifa.
Harefuah. 1989 Sep;117(5-6):126-8.
Hepatic involvement in juvenile rheumatoid arthritis of the systemic type (JRA) is a diagnostic challenge because of the varied clinical picture it presents. We describe a 21-year-old woman in whom JRA had started at the age of 4 years as an illness resembling familial Mediterranean fever. This long-standing illness was complicated by liver damage and needle biopsy showed massive hepatic deposition of amyloid. It is possible that this patient may have developed JRA as a complication of familial Mediterranean fever.
全身性幼年类风湿关节炎(JRA)中的肝脏受累因其呈现的多样临床表现而成为一个诊断难题。我们描述了一名21岁女性,她4岁时开始患JRA,起初表现类似家族性地中海热。这种长期疾病因肝脏损害而变得复杂,穿刺活检显示肝脏有大量淀粉样物质沉积。该患者有可能是在家族性地中海热的基础上并发了JRA。