Patra Bichitra Nanda, Khandelwal Sudhir K, Chadda Rakesh K, Ramakrishnan Lakshmy
Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.
Department of Cardiac Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Indian J Psychol Med. 2014 Apr;36(2):129-33. doi: 10.4103/0253-7176.130968.
Lower levels of circulating lipid fractions and cholesterol are risk factors for impulsivity and depressive disorder. A lower level of serum cholesterol is also associated with patients presenting with history of self-harm.
A total of 30 depressive patients and 30 healthy matched control subjects were recruited from the department of Psychiatry of a tertiary care hospital. We measured serum total cholesterol (TC), low-density lipoprotein (LDL) and high-density lipoprotein cholesterol and triglyceride levels of both patient and control group.
The serum TC and LDL-cholesterol levels were found to be significantly lower in study group than that of control group.
Lower levels of serum cholesterol are associated with depressive disorder.
循环脂质组分和胆固醇水平较低是冲动和抑郁症的危险因素。血清胆固醇水平较低也与有自残史的患者有关。
从一家三级护理医院的精神科招募了30名抑郁症患者和30名健康匹配对照者。我们测量了患者组和对照组的血清总胆固醇(TC)、低密度脂蛋白(LDL)、高密度脂蛋白胆固醇和甘油三酯水平。
研究组的血清TC和LDL胆固醇水平显著低于对照组。
血清胆固醇水平较低与抑郁症有关。