Edwards Martin O, Watkins William John, Kotecha Sarah J, Halcox Julian P J, Dunstan Frank D, Henderson Alexander John, Kotecha Sailesh
Department of Child Health, School of Medicine, Cardiff University, Cardiff, UK.
Acta Paediatr. 2014 Sep;103(9):904-12. doi: 10.1111/apa.12699. Epub 2014 Jun 19.
Preterm birth, low birth weight and poor foetal nutrition have been linked to cardiovascular disease, but the underlying mechanisms remain unclear. We explored prematurity and vascular function by studying a UK cohort of 14 049 children and conducting a systematic review.
Systolic blood pressure was higher in subjects born preterm than term, but there were no differences in endothelial dysfunction or arterial stiffness. The systematic review revealed no clear association between prematurity and vascular function.
早产、低出生体重和胎儿营养不良与心血管疾病有关,但潜在机制尚不清楚。我们通过研究一个包含14049名儿童的英国队列并进行系统评价,来探讨早产与血管功能之间的关系。
早产出生的受试者收缩压高于足月出生者,但在内皮功能障碍或动脉僵硬度方面无差异。系统评价未发现早产与血管功能之间存在明确关联。