Suppr超能文献

二分计数的逻辑回归

Logistic regression for dichotomized counts.

作者信息

Preisser John S, Das Kalyan, Benecha Habtamu, Stamm John W

机构信息

Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA

Department of Statistics, University of Calcutta, Kolkata, India.

出版信息

Stat Methods Med Res. 2016 Dec;25(6):3038-3056. doi: 10.1177/0962280214536893. Epub 2014 May 26.

Abstract

Sometimes there is interest in a dichotomized outcome indicating whether a count variable is positive or zero. Under this scenario, the application of ordinary logistic regression may result in efficiency loss, which is quantifiable under an assumed model for the counts. In such situations, a shared-parameter hurdle model is investigated for more efficient estimation of regression parameters relating to overall effects of covariates on the dichotomous outcome, while handling count data with many zeroes. One model part provides a logistic regression containing marginal log odds ratio effects of primary interest, while an ancillary model part describes the mean count of a Poisson or negative binomial process in terms of nuisance regression parameters. Asymptotic efficiency of the logistic model parameter estimators of the two-part models is evaluated with respect to ordinary logistic regression. Simulations are used to assess the properties of the models with respect to power and Type I error, the latter investigated under both misspecified and correctly specified models. The methods are applied to data from a randomized clinical trial of three toothpaste formulations to prevent incident dental caries in a large population of Scottish schoolchildren.

摘要

有时人们会关注一个二分结果,该结果表明计数变量是正数还是零。在这种情况下,应用普通逻辑回归可能会导致效率损失,在假定的计数模型下,这种损失是可以量化的。在这种情况下,人们研究了一种共享参数障碍模型,以便在处理有许多零值的计数数据时,更有效地估计与协变量对二分结果的总体影响相关的回归参数。一个模型部分提供一个逻辑回归,包含主要感兴趣的边际对数优势比效应,而一个辅助模型部分根据干扰回归参数描述泊松或负二项过程的平均计数。相对于普通逻辑回归,评估了两部分模型的逻辑模型参数估计量的渐近效率。使用模拟来评估模型在功效和I型错误方面的性质,后者在错误指定和正确指定的模型下进行研究。这些方法应用于一项随机临床试验的数据,该试验涉及三种牙膏配方,旨在预防大量苏格兰学童的新发龋齿。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验