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抗生素在体外控制细胞壁降解酶产生及体内疾病发展方面的作用。

Effect of antibiotics in controlling the production of cell wall degrading enzymes in vitro and disease development in vivo.

作者信息

Chopra S, Mehta A, Mehta P

出版信息

Hindustan Antibiot Bull. 1989 Aug-Nov;31(3-4):83-9.

PMID:2486272
Abstract

Production of cellulolytic, proteolytic and pectolytic enzymes by all the three isolates of A. niger was inhibited by all the tested antibiotics. Nystatin (500 ppm) could cause complete inhibition of PG enzyme production, whereas PMG production was checked by amoxicillin, nystatin, chloramphenicol and raficillin at 100 ppm concentration. All the antibiotics at 500 ppm concentration checked the cellulase production in all the three isolates of A. niger. Nystatin and raficillin (100 ppm) completely controlled the protease production in all the three isolates of A. niger. A positive correlation was observed with enzyme production and mycelial biomass in three isolates of A. niger, All the antibiotics at both the concentrations (100 and 500 ppm) could also check the rottening in all the three fruits in vivo conditions.

摘要

所有测试的抗生素均抑制了黑曲霉的三种分离株产生纤维素酶、蛋白酶和果胶酶。制霉菌素(500 ppm)可完全抑制多聚半乳糖醛酸酶的产生,而阿莫西林、制霉菌素、氯霉素和瑞弗西林在100 ppm浓度时可抑制多聚半乳糖醛酸甲酯酶的产生。所有500 ppm浓度的抗生素均抑制了黑曲霉三种分离株的纤维素酶产生。制霉菌素和瑞弗西林(100 ppm)完全抑制了黑曲霉三种分离株的蛋白酶产生。在黑曲霉的三种分离株中,酶产生与菌丝体生物量之间存在正相关。两种浓度(100和500 ppm)的所有抗生素在体内条件下也均可抑制所有三种果实的腐烂。

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