Department of Breast and Endocrine Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
J Surg Oncol. 2014 Sep;110(3):265-9. doi: 10.1002/jso.23642. Epub 2014 May 26.
There is limited information regarding rates of and risk factors for regional lymphatic recurrence (RLR) after salvage surgery for ipsilateral breast tumor recurrence (IBTR) without local treatment for the regional lymphatic basin.
One hundred two patients, who underwent salvage breast surgery without local treatment for the regional lymphatic basin (surgery or radiotherapy) for IBTR that relapsed after breast-conserving surgery for primary breast cancer, were reviewed retrospectively to examine the rate of and risk factors for RLR.
Of the 102 patients, 9 patients (8.8%) had RLR with a median follow-up period of 3.7 years after salvage breast surgery for IBTR. The estrogen receptor (ER) status and lymphovascular invasion of the recurrent breast tumor were both independent predictive factors of RLR (P = 0.04 and 0.02, respectively).
The rate of RLR was not low in patients with IBTR who received salvage breast surgery only without any treatment for the regional lymphatic basin. The ER status and lymphovascular invasion of the recurrent breast tumor were predictive factors of RLR.
对于保乳手术后同侧乳腺肿瘤复发（IBTR）且未对区域淋巴结进行局部治疗的患者，挽救性乳房手术后区域淋巴结局部复发（RLR）的发生率和风险因素的相关信息有限。
回顾性分析了 102 例因原发性乳腺癌保乳手术后复发而接受挽救性乳房手术但未对区域淋巴结（手术或放疗）进行局部治疗的 IBTR 患者，以检查 RLR 的发生率和风险因素。
在 102 例患者中，有 9 例（8.8%）患者在挽救性乳房手术治疗 IBTR 后 3.7 年的中位随访期间发生 RLR。复发性乳腺肿瘤的雌激素受体（ER）状态和脉管侵犯均为 RLR 的独立预测因素（P=0.04 和 0.02）。
对于仅接受挽救性乳房手术而未对区域淋巴结进行任何治疗的 IBTR 患者，RLR 的发生率并不低。复发性乳腺肿瘤的 ER 状态和脉管侵犯是 RLR 的预测因素。
