Laboratory of Polymer Chemistry, Department of Polymer Materials, College of Materials Science and Engineering, Department of Chemistry, Shanghai University, Materials Building Room 447, Nanchen Street 333, Shanghai, 200444, China.
Macromol Rapid Commun. 2014 Aug;35(15):1326-31. doi: 10.1002/marc.201400158. Epub 2014 May 26.
Self-assembly of C3 discotic molecules bearing dipeptide pendants into helical supramolecular polymers is investigated. The dipeptides are constituted from glycine and alanine with altered sequence, aiming at modulating the steric hindrance and examining the steric effects on the assembly. This steric hindrance effect is further illustrated with a dipeptide formed from glycine and valine, which carries a much larger isopropyl side unit. Their supramolecular polymerization is examined in various organic solvents and at different temperatures. The assembly morphology is directly visualized with atomic force microscopy. It is found that small changes in the dipeptide motifs in combination with solvent structure and the solution concentrations lead to different expression of the supramolecular assembly.
研究了带有二肽侧基的 C3 盘状分子的自组装，形成螺旋超分子聚合物。这些二肽由甘氨酸和丙氨酸组成，序列发生了改变，旨在调节空间位阻，并考察空间位阻对组装的影响。这种空间位阻效应进一步用由甘氨酸和缬氨酸组成的二肽来说明，它带有一个更大的异丙基侧基。在不同的有机溶剂和不同的温度下，对它们的超分子聚合进行了研究。通过原子力显微镜直接观察组装形态。结果发现，二肽基序的微小变化以及溶剂结构和溶液浓度的变化导致超分子组装的不同表达。
