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[应用天然高矿化溴碘盐水治疗银屑病患者的临床结果及脂质过氧化动力学]

[The clinical results and lipid peroxidation dynamics in the patients presenting with psoriasis treated by the applications of a natural highly mineralized bromine-iodine brine].

作者信息

El'kin V D, Koriukina I P, Datskovskiĭ Ia S, Plotnikova E V

出版信息

Vopr Kurortol Fizioter Lech Fiz Kult. 2014 Mar-Apr(2):38-42.

PMID:24864488
Abstract

The authors report the results of the treatment of 64 patients presenting with psoriasis by the applications of a natural highly mineralized bromine-iodine brine. The method has been shown to be highly efficacious and safe. It allowed the clinical remission and marked improvement of the patients' clinical conditions to be achieved in 48 (77.4%) cases compared with 10 (27.8%) cases among the patients of the control group. Exacerbation was documented in a single patient with psoriatic erythrodermia. All the patients showed the normal results of general and biochemical clinical analyses of blood and urea throughout the study period. The applications of the natural highly mineralized bromine-iodine brine exerted the normalizing action on seven of the 8 characteristics of the lipid peroxidation process. It is maintained that the high effectiveness of the method in question can be accounted not only by the reflectory and humoral mechanisms of action of highly mineralized bromine-iodine brine but also by the marked exhaustion of the functional reserves of the mast cells under effect of the applications. It is concluded that an advantage of the proposed approach over standard balneotherapeutic procedures consists of the possibility to employ it not only at the base of a spa and health resort facility but also in a different setting with the involvement of the patients suffering from progressive psoriasis.

摘要

作者报告了应用天然高矿化溴碘盐水治疗64例银屑病患者的结果。该方法已被证明具有高效性和安全性。与对照组患者中的10例(27.8%)相比,它使48例(77.4%)患者实现了临床缓解并显著改善了临床状况。仅1例银屑病红皮病患者出现病情加重。在整个研究期间,所有患者的血液和尿素的一般及生化临床分析结果均正常。天然高矿化溴碘盐水的应用对脂质过氧化过程的8个特征中的7个发挥了正常化作用。有人认为,该方法的高效性不仅可以归因于高矿化溴碘盐水的反射性和体液作用机制,还可以归因于应用该盐水后肥大细胞功能储备的明显耗竭。结论是,与标准浴疗程序相比,该方法的优势在于不仅可以在温泉疗养胜地设施的基础上使用,还可以在不同环境中用于患有进行性银屑病的患者。

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