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糖尿病性肌萎缩一例中的毛细血管改变及单核细胞浸润

Capillary alterations and mononuclear cell infiltrate in a case of diabetic amyotrophy.

作者信息

Márquez A, Torres S H, Finol H J, Figueroa L, de Blanco M C

出版信息

Acta Cient Venez. 1989;40(4):251-3.

PMID:2486453
Abstract

A 56 year-old man with diabetes mellitus and pain, muscle weakness and wasting in both thighs, of three months duration, had a diagnosis of diabetic amyotrophy. The ultrastructural study of a biopsy from quadriceps femoris muscle showed usual findings in muscle fibers and two not previously reported alterations: capillary necrosis and mononuclear cell infiltration consisting of macrophages, lymphocytes and plasma cells. The etiopathogenesis of muscle damage in diabetic amyotrophy is discussed.

摘要

一名56岁男性,患有糖尿病,双大腿疼痛、肌肉无力及萎缩3个月,诊断为糖尿病性肌萎缩。股四头肌活检的超微结构研究显示肌纤维有常见表现,还有两种以前未报道的改变:毛细血管坏死以及由巨噬细胞、淋巴细胞和浆细胞组成的单核细胞浸润。本文讨论了糖尿病性肌萎缩中肌肉损伤的病因发病机制。

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