Suppr超能文献

气泡注入对丁卡因重比重液和布比卡因腰麻时阻滞特性的影响。

Influence of barbotage on block characteristics during spinal anesthesia with hyperbaric tetracaine and bupivacaine.

作者信息

Janik R, Dick W, Stanton-Hicks M D

机构信息

Department of Anesthesiology, Johannes Gutenberg University Hospital, Mainz, Federal Republic of Germany.

出版信息

Reg Anesth. 1989 Jan-Feb;14(1):26-30.

PMID:2486582
Abstract

Barbotage is the aspiration of the injected volume back into the syringe followed by reinjection twice, with 0.5 ml increases in each aspirated volume. The effects of this technique versus injection without barbotage, on the spinal anesthetic spread of 0.5% tetracaine or 0.5% bupivacaine in 5% glucose 4 ml each, were investigated in 80 men undergoing urologic surgery. The local anesthetic solutions were randomly injected into four groups of 20 patients each, and the anesthetic profile of each solution was then evaluated in a double-blind fashion for the two techniques (barbotage/without barbotage) by an independent observer. In the tetracaine groups, barbotage was associated with a higher dermatome level and shorter time to reach this compared with tetracaine without barbotage. Barbotage caused the latency of bupivacaine to be shorter, but the actual time difference was small and clinically not relevant. Comparing tetracaine and bupivacaine, tetracaine with barbotage achieved a higher segmental level. Time to highest dermatome, however, was shorter for bupivacaine with barbotage compared with tetracaine with barbotage. Barbotage shortened the onset of 3+ motor block with bupivacaine. This difference was statistically significant. Results suggest that barbotage is useful to shorten the time for full development of analgesia when using 0.5% hyperbaric tetracaine. Barbotage with 0.5% hyperbaric bupivacaine, however, has the advantage of intensifying and shortening the onset time of a complete motor block.

摘要

回抽法是将注入的液体回抽到注射器中,然后再注入两次,每次回抽的液体量增加0.5毫升。在80例接受泌尿外科手术的男性患者中,研究了这种技术与不采用回抽法注射相比,对分别含0.5%丁卡因或0.5%布比卡因的4毫升5%葡萄糖溶液脊髓麻醉扩散的影响。局部麻醉溶液被随机注入四组,每组20例患者,然后由一名独立观察者以双盲方式评估两种技术(回抽法/不采用回抽法)下每种溶液的麻醉情况。在丁卡因组中,与不采用回抽法的丁卡因相比,回抽法与更高的皮节水平相关,且达到该水平的时间更短。回抽法使布比卡因的潜伏期缩短,但实际时间差异较小,在临床上不相关。比较丁卡因和布比卡因,采用回抽法的丁卡因达到的节段水平更高。然而,与采用回抽法的丁卡因相比,采用回抽法的布比卡因达到最高皮节的时间更短。回抽法缩短了布比卡因导致3级以上运动阻滞的起效时间。这种差异具有统计学意义。结果表明,在使用0.5%重比重丁卡因时,回抽法有助于缩短镇痛完全起效的时间。然而,0.5%重比重布比卡因采用回抽法具有增强和缩短完全运动阻滞起效时间的优势。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验