Kuroda Utako, Inoue Toshihiro, Awai-Kasaoka Nanako, Shobayashi Kohei, Kojima Sachi, Tanihara Hidenobu
Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Clin Ophthalmol. 2014 May 15;8:949-54. doi: 10.2147/OPTH.S61342. eCollection 2014.
To compare the surgical outcomes of limbal-based and fornix-based trabeculectomy in eyes with a history of ocular incisional surgery.
Twenty-six eyes underwent limbal-based trabeculectomy (group LB), and were condition matched with 26 eyes that received fornix-based trabeculectomy (group FB). Surgical failure was recorded retrospectively if the intraocular pressure value was either ≥21, ≥18, and ≥15 mmHg (conditions A, B, and C, respectively) or <4 mmHg or if the patient required additional glaucoma surgery. Kaplan-Meier survival curve analysis was used to assess surgical failure.
For condition A, the 2 year surgical success probabilities were 75.0% and 63.9% in groups FB and LB, respectively (P=0.124). The corresponding values were 55.0% and 61.7% (P=0.638) in condition B, and 55.0% and 57.0% (P=0.454) in condition C. The rates of bleb leakage, hypotony, choroidal detachment, and bleb-related infection were 11.5%, 26.9%, 50.0%, and 7.7% in group LB, respectively. The corresponding values in group FB were 30.8%, 23.1%, 46.2%, and 0.0%, which were not statistically different between the two groups.
No significant differences in surgical outcomes were observed between limbal-based and fornix-based trabeculectomy for patients with a history of incisional ocular surgeries.
比较在有眼部切开手术史的眼中,以角膜缘为基底的小梁切除术和以穹窿为基底的小梁切除术的手术效果。
26只眼接受了以角膜缘为基底的小梁切除术(LB组),并与26只接受以穹窿为基底的小梁切除术的眼(FB组)进行条件匹配。如果眼压值≥21、≥18和≥15 mmHg(分别为A、B和C条件)或<4 mmHg,或者患者需要额外的青光眼手术,则回顾性记录手术失败情况。采用Kaplan-Meier生存曲线分析来评估手术失败情况。
对于A条件,FB组和LB组的2年手术成功率分别为75.0%和63.9%(P = 0.124)。B条件下相应的值分别为55.0%和61.7%(P = 0.638),C条件下分别为55.0%和57.0%(P = 0.454)。LB组的滤过泡渗漏、低眼压、脉络膜脱离和滤过泡相关感染率分别为11.5%、26.9%、50.0%和7.7%。FB组的相应值分别为30.8%、23.1%、46.2%和0.0%,两组之间无统计学差异。
对于有眼部切开手术史的患者,以角膜缘为基底的小梁切除术和以穹窿为基底的小梁切除术在手术效果上无显著差异。