Shinozuka N, Masuda H, Okai T, Kuwabara Y, Mizuno M
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo, Japan.
Fetal Ther. 1989;4(2-3):97-109. doi: 10.1159/000263431.
Fetal behavior was studied in 17 cases of fetal abnormalities including nonimmune hydrops fetalis and in 11 cases of intrauterine growth retardation (IUGR) in comparison to 30 healthy fetuses. Breathing movements, rapid eye movements and trunk movements were observed ultrasonically and analyzed using a computer-assisted system. The cases with central nervous system anomalies showed a markedly different behavioral pattern. In the fetal abnormalities without chromosomal anomalies, the cases without major behavioral disorders were cured by neonatal treatment. IUGR cases with decreased trunk, breathing and REM period were finally diagnosed as having fetal distress by fetal heart rate monitoring. The findings on fetal behavior hint at the possibility of diagnosing abnormalities in neural development as well as in well-being.
对17例包括非免疫性胎儿水肿在内的胎儿异常病例以及11例宫内生长受限(IUGR)病例的胎儿行为进行了研究,并与30例健康胎儿进行了比较。通过超声观察呼吸运动、快速眼动和躯干运动,并使用计算机辅助系统进行分析。中枢神经系统异常的病例表现出明显不同的行为模式。在无染色体异常的胎儿异常病例中,无主要行为障碍的病例经新生儿治疗后治愈。躯干、呼吸和快速眼动期减少的IUGR病例最终通过胎儿心率监测被诊断为胎儿窘迫。胎儿行为的研究结果提示了诊断神经发育异常以及胎儿健康状况的可能性。