Anunobi C C, Jagun O E, Agboola A O, Akintola P A, Andu B A
Department of Anatomic and Molecular Pathology, College of Medicine, University of Lagos. PMB 12003,Lagos.
West Afr J Med. 2014 Jan-Mar;33(1):7-11.
To ascertain the pattern and frequency of female genital malignancies among the different age groups, the common presenting complaints of cervical cancer patients and stages of presentation as seen in Sagamu, Ogun State.
A retrospective analysis of reports of formalin fixed paraffin embedded tissue blocks and slides of all female genital samples received at Morbid Anatomy & Histopathology Department of Olabisi Onabanjo University Teaching Hospital, Sagamu from January 1st, 2003 to June 30th, 2012. The personal data and clinical history were retrieved from laboratory forms and the patients' case files.
The age range of patients whose specimens were reviewed was between 21-85 years. Cancers of the cervix accounted for majority (65.1%) of the cases followed by ovarian cancer (23.2%) and cancer involving the uterus (10.5%). Sixty-six percent of the cervical cancer patients are 50 years and above. Majority of the cervical cancer cases (82.2%) were squamous cell carcinoma. The common clinical features were post-menopausal bleeding (53.3%), vaginal discharge (43.3%), and intermenstrual bleeding (16.7%). The interval between onset of symptoms and seeking of healthcare was 6.7 ± 3.66 months. Stage IIIB cervical cancer was seen in 40% of the cervical cancer patients analyzed while no case of Stage IA was seen. Ninety-three percent of these patients were referred for radiotherapy.
Cancer of the cervix is the commonest gynaecological malignancy and most patients presented late. Free or government subsidized cervical cancer screening programmes and awareness campaign is highly recommended.
确定奥贡州萨加穆地区不同年龄组女性生殖系统恶性肿瘤的类型和发生率、宫颈癌患者的常见主诉及就诊时的分期。
对2003年1月1日至2012年6月30日期间在奥拉比西·奥纳班乔大学教学医院萨加穆分院病理解剖与组织病理学科接收的所有女性生殖系统样本的福尔马林固定石蜡包埋组织块及玻片报告进行回顾性分析。从实验室表格和患者病历中获取个人数据及临床病史。
所审查标本的患者年龄范围在21 - 85岁之间。宫颈癌占病例的大多数（65.1%），其次是卵巢癌（23.2%）和子宫癌（10.5%）。66%的宫颈癌患者年龄在50岁及以上。大多数宫颈癌病例（82.2%）为鳞状细胞癌。常见临床特征为绝经后出血（53.3%）、阴道分泌物增多（43.3%）和经间期出血（16.7%）。症状出现至寻求医疗保健的间隔时间为6.7 ± 3.66个月。在分析的宫颈癌患者中，40%为IIIB期宫颈癌，未发现IA期病例。这些患者中有93%被转诊接受放疗。
宫颈癌是最常见的妇科恶性肿瘤，大多数患者就诊时已处于晚期。强烈建议开展免费或政府补贴的宫颈癌筛查项目及提高公众意识的活动。
