Rae J L, Cooper K E
Department of Physiology, Mayo Foundation, Rochester, MN 55905.
Lens Eye Toxic Res. 1989;6(4):833-43.
Before hatching, chick embryos show a high incidence of inwardly rectifying potassium channels and calcium-activated potassium channels in the apical membrane of their lens epithelium. Subsequent to hatching, these channel types disappear while, at about the same time, a new calcium insensitive maxi potassium channel appears. This new channel shows several properties in common with the calcium-activated maxi potassium channels but is different in its conductive and gating properties.
在孵化前,鸡胚胎晶状体上皮细胞顶端膜中内向整流钾通道和钙激活钾通道的发生率很高。孵化后,这些通道类型消失,与此同时,一种新的对钙不敏感的大电导钾通道出现。这种新通道与钙激活大电导钾通道有几个共同特性,但在其传导和门控特性方面有所不同。