Department of Internal Medicine, Division of Nephrology, UT Southwestern Medical Center, Dallas, Texas.
Am J Med Sci. 2014 Sep;348(3):250-61. doi: 10.1097/MAJ.0000000000000283.
Peritoneal dialysis (PD) continues to be underutilized in the United States, even though it is less expensive, provides better quality of life and has better outcomes compared with hemodialysis. The reasons for low utilization of PD are influenced by complex psychosocial and economic factors, lack of physician training, physician bias and inadequate pre-end-stage renal disease care and education to the patients. Providing quality pre-end-stage renal disease education to patients and families and improving education and training of physician in PD, so that they become comfortable with the therapy, are of paramount importance to increase PD growth. Minimizing episodes of PD-related infections and noninfectious complications, preserving peritoneal membrane using more biocompatible solutions and drugs, such as angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, and careful management of volume status can reduce the loss of PD patients to hemodialysis. Timely surgical interventions can prevent the malfunction and loss of PD catheters. Consolidating smaller PD facilities in a given geographical area into a single large PD center can further improve PD outcomes and PD growth. Finally, with the introduction of bundled payment for dialysis services, PD may emerge as a cost-effective therapy and rekindle interest in the dialysis community to consider PD as a better renal replacement therapy option.
腹膜透析(PD)在美国的应用仍然不足,尽管与血液透析相比,PD 更便宜、生活质量更好、结局更好。PD 利用率低的原因受到复杂的社会心理和经济因素、医生培训不足、医生偏见以及对患者终末期肾病前的护理和教育不足的影响。为患者和家属提供优质的终末期肾病前教育,并提高医生在 PD 方面的教育和培训,使他们对治疗感到舒适,对于增加 PD 的发展至关重要。尽量减少 PD 相关感染和非感染性并发症的发生,使用更具生物相容性的溶液和药物(如血管紧张素转换酶抑制剂和血管紧张素受体阻滞剂)来保护腹膜,以及仔细管理容量状态,可以减少 PD 患者向血液透析的流失。及时进行手术干预可以防止 PD 导管发生故障和丢失。将特定地理区域内较小的 PD 设施合并到一个单一的大型 PD 中心,可以进一步改善 PD 的结局和 PD 的发展。最后,随着透析服务捆绑式支付的引入,PD 可能成为一种具有成本效益的治疗方法,并重新激发透析界的兴趣,将 PD 视为一种更好的肾脏替代治疗选择。