Kriett J M, Tarazi R Y, Kaye M P
University of California, San Diego.
Clin Transpl. 1989:45-53.
The International Society of Heart Transplantation Registry has now received data on almost 12,000 transplants including over 11,000 heart transplants and almost 600 heart-lung and 100 lung transplants. Recently, a plateau in number of transplants per year has become evident. It appears that further growth is now limited by donor supply. Operative mortality and long-term survival rates continue to show gradual improvement. Organ preservation and other intraoperative complications remain a major factor associated with operative mortality, especially in heart-lung and lung transplantation. Infection and rejection remain the most common causes of early and late deaths. An increasing number of patients have now received second transplants. At the present time, results with retransplantation are significantly worse than for the initial transplant.
国际心脏移植学会登记处现已收到近12000例移植手术的数据,其中包括11000多例心脏移植手术、近600例心肺移植手术和100例肺移植手术。最近,每年移植手术数量趋于平稳已变得明显。看来,进一步增长目前受到供体供应的限制。手术死亡率和长期生存率继续呈现逐步改善的趋势。器官保存及其他术中并发症仍然是与手术死亡率相关的主要因素,尤其是在心肺移植和肺移植手术中。感染和排斥反应仍然是早期和晚期死亡的最常见原因。现在越来越多的患者接受了二次移植。目前,再次移植的结果明显比初次移植差。