Le Roy Audrey, Pasquier Pierre, Savard Dillon, Bugier Sarah, Merat Stéphane, Pilo Jean-Etienne, Delacour Hervé
Bégin Military Teaching Hospital, Intensive Care Unit, Saint Mandé, France.
Family Medicine Residency, David Grant Medical Center, California, USA.
Ann Biol Clin (Paris). 2014 May-Jun;72(3):367-70. doi: 10.1684/abc.2014.0953.
Paraneoplastic syndromes (PNPs) refer to cancer-associated signs and symptoms arising in organs and tissues that are remote from the cancer and unrelated to metastasis. Currently the best described PNPs are attributed to tumor secretion of functional peptides and hormones or immune cross-reactivity between tumor and normal host tissues. Paraneoplastic hematologic syndromes are observed more rarely. Here we report a case of paraneoplastic granulocytosis in an advanced lung cancer patient.
副肿瘤综合征（PNPs）是指在远离癌症且与转移无关的器官和组织中出现的与癌症相关的体征和症状。目前，描述最为详尽的副肿瘤综合征归因于肿瘤分泌功能性肽和激素，或肿瘤与正常宿主组织之间的免疫交叉反应。副肿瘤性血液系统综合征则较为少见。在此，我们报告一例晚期肺癌患者并发副肿瘤性粒细胞增多症的病例。
