Lanzola Giordano, Scarpellini Stefania, Di Palma Federico, Toffanin Chiara, Del Favero Simone, Magni Lalo, Bellazzi Riccardo
Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy
Department of Civil Engineering and Architecture, University of Pavia, Pavia, Italy.
J Diabetes Sci Technol. 2014 Mar;8(2):216-224. doi: 10.1177/1932296814522120. Epub 2014 Mar 2.
The increase in the availability and reliability of network connections lets envision systems supporting a continuous remote monitoring of clinical parameters useful either for overseeing chronic diseases or for following clinical trials involving outpatients. We report here the results achieved by a telemedicine infrastructure that has been linked to an artificial pancreas platform and used during a trial of the AP@home project, funded by the European Union. The telemedicine infrastructure is based on a multiagent paradigm and is able to deliver to the clinic any information concerning the patient status and the operation of the artificial pancreas. A web application has also been developed, so that the clinic staff and the researchers involved in the design of the blood glucose control algorithms are able to follow the ongoing experiments. Albeit the duration of the experiments in the trial discussed in the article was limited to only 2 days, the system proved to be successful for monitoring patients, in particular overnight when the patients are sleeping. Based on that outcome we can conclude that the infrastructure is suitable for the purpose of accomplishing an intelligent monitoring of an artificial pancreas either during longer trials or whenever that system will be used as a routine treatment.
网络连接可用性和可靠性的提高,使人们能够设想出这样的系统:它能支持对临床参数进行持续远程监测,这对慢性病监管或跟踪涉及门诊患者的临床试验都很有用。我们在此报告一个远程医疗基础设施所取得的成果,该设施已与一个人工胰腺平台相连,并在由欧盟资助的“在家使用人工胰腺(AP@home)”项目试验中得到应用。该远程医疗基础设施基于多智能体范式,能够向诊所提供任何有关患者状态和人工胰腺运行情况的信息。还开发了一个网络应用程序,以便参与血糖控制算法设计的诊所工作人员和研究人员能够跟踪正在进行的实验。尽管本文所讨论试验中的实验持续时间仅限制为两天,但该系统在监测患者方面被证明是成功的,尤其是在患者夜间睡眠时。基于这一结果,我们可以得出结论,该基础设施适用于在更长时间的试验期间或每当该系统用作常规治疗时对人工胰腺进行智能监测的目的。