Lavery Lawrence A, Murdoch Douglas P, Kim Paul J, Fontaine Javier La, Thakral Gaurav, Davis Kathryn E
Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas TX, USA
Department of Surgery, Scott and White Hospital, Temple, TX, USA.
J Diabetes Sci Technol. 2014 Mar;8(2):346-349. doi: 10.1177/1932296813519012. Epub 2014 Feb 18.
This study was a prospective cohort study to evaluate negative pressure wound therapy (NPWT) with low pressure and a gauze dressing to treat diabetic foot wounds. Thirty patients with diabetic foot wounds were consented to a prospective study to evaluate wound closure and complications to evaluate NPWT with low pressure (80 mmHg) and a gauze dressing interface (EZCare, Smith and Nephew) for up to 5 weeks. NPWT was changed 3 times a week. Study subjects were evaluated once a week for adverse events and wound measurements. Of study subjects, 43% attained at least a 50% wound area reduction after 4 weeks of therapy. Our results suggest that a high rate of wound closure could be expected with low pressure and a gauze interface.
本研究是一项前瞻性队列研究，旨在评估低压联合纱布敷料的负压伤口治疗（NPWT）对糖尿病足伤口的疗效。30例糖尿病足伤口患者同意参与一项前瞻性研究，以评估伤口愈合情况及并发症，该研究采用低压（80 mmHg）联合纱布敷料界面（EZCare，施乐辉公司）进行NPWT，为期5周。NPWT每周更换3次。研究对象每周接受一次不良事件评估和伤口测量。在治疗4周后，43%的研究对象伤口面积至少减少了50%。我们的结果表明，采用低压联合纱布界面可实现较高的伤口愈合率。
