Chatham W, Williams G, Moreland L, Parker J W, Ross C, Alarcón S G, Alarcón G S
Arthritis Care Res. 1989 Jun;2(2):70-4. doi: 10.1002/anr.1790020209.
To prevent damage in injected joints, it has been our policy to rest them for 48 hours. To test this assertion we randomized 30 rheumatoid arthritis (RA) patients (rest, no-rest). Results in 28 patients (63 joints: 27 rest and 36 no-rest) are presented. Joint evaluation was performed at baseline and at 48 hours (pain/tenderness, swelling and range of motion). Two analyses were conducted, the first included all joints, and the second only joint pairs. In both cases measurements at 48 hours were comparable for the rest and no rest group for both upper and lower extremity joints (pain/tenderness/swelling and range of motion). At a later follow up (average 10 months) there were no differences in any of the parameters examined. Our study suggests that rest is not essential for intraarticular corticosteroids to be beneficial, at least in an inpatient setting. The applicability of our data to an outpatient population remains to be determined.
为防止注射关节受损，我们的政策是让其休息48小时。为验证这一说法，我们将30名类风湿性关节炎（RA）患者随机分组（休息组、不休息组）。现报告28名患者（63个关节：27个休息关节和36个不休息关节）的结果。在基线和48小时时进行关节评估（疼痛/压痛、肿胀和活动范围）。进行了两项分析，第一项分析包括所有关节，第二项分析仅包括关节对。在这两种情况下，休息组和不休息组的上下肢关节在48小时时的测量结果（疼痛/压痛/肿胀和活动范围）具有可比性。在随后的随访（平均10个月）中，所检查的任何参数均无差异。我们的研究表明，至少在住院环境中，休息对于关节内注射皮质类固醇发挥益处并非必不可少。我们的数据对门诊患者的适用性仍有待确定。
