Paszkowski T, Sikorski R, Kozak A, Kowalski B, Jakubik J
Pol Tyg Lek. 1989;44(46-48):961-3.
Human milk nitrates and nitrites were assayed colorimetrically. Colostrum samples were collected on the 3rd postpartum day from 59 women inhabiting Puławy region and being potentially exposed to nitrogen compounds emitted from the industrial sources. Thirty five Lublin inhabitants serving as a control group were matched in age, parity and duration of pregnancy. Geometric mean value of nitrates and nitrites concentration in the human milk being 2.83 mg/L and 0.46 mg/L, respectively were higher in the examined group than those in the control group /2.76 mg/L and 0.32 mg/L/ but difference was statistically insignificant. Ratio of nitrates and nitrites in the examined samples was 7.38 on the average and the concentration of those compounds was related statistically significantly /p less than 0.001/. The average daily intake of nitrates and nitrites by the breast-fed neonates was 0.12 mg/kg body weight and 0.02 mg/kg body weight, respectively. These values did not exceed corresponding ADI recommended by the Joint Expert Committee of FAO/WHO in none case. Significantly positive correlation of examined mothers' age and parity with nitrates content in their colostrum was seen. In view of the obtained results is may be assumed that the examined colostrum samples contain low amounts of both nitrates and nitrites.
采用比色法测定人乳中的硝酸盐和亚硝酸盐含量。从居住在普瓦维地区、可能接触工业源排放的氮化合物的59名妇女产后第3天采集初乳样本。选取35名卢布林居民作为对照组，在年龄、产次和孕期方面进行匹配。检测组人乳中硝酸盐和亚硝酸盐的几何平均浓度分别为2.83毫克/升和0.46毫克/升，高于对照组（2.76毫克/升和0.32毫克/升），但差异无统计学意义。检测样本中硝酸盐与亚硝酸盐的平均比值为7.38，且这些化合物的浓度具有显著统计学相关性（P<0.001）。母乳喂养新生儿的硝酸盐和亚硝酸盐平均每日摄入量分别为0.12毫克/千克体重和0.02毫克/千克体重。在任何情况下，这些数值均未超过粮农组织/世卫组织联合专家委员会建议的相应每日允许摄入量。观察到受检母亲的年龄和产次与其初乳中硝酸盐含量呈显著正相关。鉴于所获结果，可以假定所检测的初乳样本中硝酸盐和亚硝酸盐含量均较低。
