Department of Physics, Shanghai University, Shanghai 200444, China.
Department of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA.
J Biomech. 2014 Jul 18;47(10):2244-8. doi: 10.1016/j.jbiomech.2014.04.054. Epub 2014 May 14.
In this study, a theoretical framework for simulation of fracture of bone and bone-like materials is provided. An expanded cohesive zone model with thermodynamically consistent framework has been proposed and used to investigate the crack growth resistance of bone and bone-like materials. The reversible elastic deformation, irreversible plastic deformation caused by large deformation of soft protein matrix, and damage evidenced by the material separation and crack nucleation in the cohesive zone, were all taken into account in the model. Furthermore, the key mechanisms in deformation of biocomposites consisting of mineral platelets and protein interfacial layers were incorporated in the fracture process zone in this model, thereby overcoming the limitations of previous cohesive zone modeling of bone fracture. Finally, applications to fracture of cortical bone and human dentin were presented, which showed good agreement between numerical simulation and reported experiments and substantiated the effectiveness of the model in investigating the fracture behavior of bone-like materials.
本研究提供了一种用于模拟骨和骨样材料断裂的理论框架。提出了一种扩展的内聚区模型，并使用该模型来研究骨和骨样材料的裂纹扩展阻力。该模型考虑了可逆弹性变形、软蛋白质基质大变形引起的不可逆塑性变形以及内聚区中材料分离和裂纹成核导致的损伤。此外，在该模型中，将由矿物质板和蛋白质界面层组成的生物复合材料的变形的关键机制纳入断裂过程区，从而克服了以前骨断裂内聚区建模的局限性。最后，将该模型应用于皮质骨和人牙本质的断裂，数值模拟与报道的实验结果吻合较好，证实了该模型在研究骨样材料断裂行为方面的有效性。
