干扰素、白细胞介素-2及其他细胞因子。
Interferon, interleukin-2, and other cytokines.
作者信息
Buchbinder Elizabeth I, McDermott David F
机构信息
Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA.
Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA.
出版信息
Hematol Oncol Clin North Am. 2014 Jun;28(3):571-83. doi: 10.1016/j.hoc.2014.02.001. Epub 2014 Apr 3.
Cytokines are a diverse group of signaling molecules with immunomodulatory activity. This article reviews the application of cytokine therapy in melanoma with a focus on interferon-α and interleukin-2. In addition, it addresses the clinical considerations of these therapies including patient selection, reduction in toxicity, and combination regimens.
细胞因子是一类具有免疫调节活性的多样化信号分子。本文综述了细胞因子疗法在黑色素瘤中的应用，重点关注干扰素-α和白细胞介素-2。此外，还讨论了这些疗法的临床考量，包括患者选择、毒性降低和联合治疗方案。
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