Cendejas Blanca R, Smith-McCune Karen K, Khan Michelle J
University of California, San Francisco, School of Medicine, San Francisco, California.
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California San Francisco, San Francisco, CA.
Am J Obstet Gynecol. 2015 Mar;212(3):291-7. doi: 10.1016/j.ajog.2014.05.039. Epub 2014 May 29.
Human papillomavirus-associated disease represents an immense public health burden worldwide. Persistent human papillomavirus infection can lead to the development of cervical dysplasia and vulvar dysplasia, both of which have been increasing in incidence in women in recent years. Numerous studies have focused on methods for screening and diagnosis of cervical dysplasia, but few have looked at the effects of treatment on women's psychological and sexual health. Even fewer studies have addressed these issues in women with vulvar dysplasia. The aim of this article was to provide a comprehensive review of the existing evidence concerning the impact of therapy for cervical and vulvar precancers on women's sexual function and sexual relationships. We performed a search of the medical literature for the time period up to and including August 2013 on PubMed. The findings from a limited number of studies to date indicate that psychosexual vulnerability increases after diagnosis and treatment of both cervical and vulvar dysplasia. More in-depth research is needed to better understand the effects of different treatment modalities on women's sexual health and relationships during and following treatment.
人乳头瘤病毒相关疾病在全球范围内构成了巨大的公共卫生负担。持续性人乳头瘤病毒感染可导致宫颈发育异常和外阴发育异常,近年来这两种疾病在女性中的发病率均呈上升趋势。众多研究聚焦于宫颈发育异常的筛查和诊断方法,但很少有研究关注治疗对女性心理和性健康的影响。针对外阴发育异常女性的此类问题的研究更是少之又少。本文旨在全面综述现有证据,探讨宫颈和外阴癌前病变治疗对女性性功能和性关系的影响。我们在PubMed上检索了截至2013年8月(含该月)的医学文献。目前有限数量的研究结果表明,宫颈和外阴发育异常的诊断和治疗后,心理性易损性会增加。需要进行更深入的研究,以更好地了解不同治疗方式在治疗期间及之后对女性性健康和性关系的影响。