Cripe Chad C, Patel Akash R, Markowitz Scott D, Behringer Tiffany S, Litman Ronald S
Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Anesthesiology & Critical Care, The Children's Hospital of Philadelphia, PA 19104, USA.
Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA; Division of Pediatric Cardiology, The Children's Hospital of Philadelphia, PA 19104, USA.
J Clin Anesth. 2014 Jun;26(4):257-63. doi: 10.1016/j.jclinane.2013.11.020. Epub 2014 Jun 2.
To perform a qualitative analysis of noncardiac patients who developed suspected intraoperative supraventricular tachycardia (SVT) during general anesthesia.
Retrospective database analysis and chart review.
Operating room of a university-affiliated children's hospital.
The records of children without cardiac disease who received general anesthesia at The Children's Hospital of Philadelphia from July 1998 through June 2011 were reviewed. Patients with heart rate values above 180 beats per minute were identified, as were specific medications or key words in the free-text fields of the anesthesia records that would be indicative of a tachyarrhythmia. Each case was reviewed by at least two authors; each patient was assigned a diagnosis classification of "highly suspicious" or "unlikely" SVT. The highly suspicious SVT cases were examined in detail to determine the specific aims.
36 subjects out of a total of 285,353 anesthetics administered during the study period were suspected by the anesthesia care team to have had an episode of intraoperative SVT: 22 were "highly suspicious" events, and 14 were "unlikely" events. The highly suspicious SVT events occurred in all phases of anesthesia, and none led to any hemodynamic instability. Effective treatments included vagal maneuvers, pharmacologic antiarrhythmics, or no treatment if the event resolved spontaneously before treatment. Six patients had outpatient follow-up and three received antiarrhythmic medications to control ongoing SVT.
SVT during the intraoperative period in noncardiac pediatric patients was uncommon. When it occurred, it was not associated with clinically significant patient morbidity. For some patients, the anesthesia unmasked a predisposition for re-entrant SVT and those patients remained on maintenance antiarrhythmic therapy following discharge home.
对在全身麻醉期间出现疑似术中室上性心动过速(SVT)的非心脏疾病患者进行定性分析。
回顾性数据库分析和病历审查。
一所大学附属医院的手术室。
回顾了1998年7月至2011年6月在费城儿童医院接受全身麻醉的无心脏病儿童的记录。确定心率值高于每分钟180次的患者,以及麻醉记录自由文本字段中表明快速心律失常的特定药物或关键词。每个病例至少由两名作者进行审查;每个患者被分配一个“高度可疑”或“不太可能”的SVT诊断分类。对高度可疑的SVT病例进行详细检查以确定具体目标。
在研究期间实施的总共285,353例麻醉中,麻醉护理团队怀疑有36例患者发生了术中SVT发作:22例为“高度可疑”事件,14例为“不太可能”事件。高度可疑的SVT事件发生在麻醉的各个阶段,且均未导致任何血流动力学不稳定。有效的治疗方法包括迷走神经手法、抗心律失常药物治疗,或者如果事件在治疗前自行缓解则不进行治疗。6例患者进行了门诊随访,3例接受了抗心律失常药物以控制持续性SVT。
非心脏儿科患者术中发生SVT并不常见。当发生时,它与临床上显著的患者发病率无关。对于一些患者,麻醉揭示了其存在折返性SVT的易感性,这些患者在出院后仍需维持抗心律失常治疗。