Division of Reproductive Medicine, Instituto Valenciano de Infertilidad, Barcelona, Spain.
Instituto Valenciano de Infertilidad and Instituto Universitario IVI, Valencia University, Valencia, Spain; Department of Obstetrics and Gynecology, School of Medicine, Valencia University, Valencia, Spain.
Fertil Steril. 2014 Jun;101(6):1531-44. doi: 10.1016/j.fertnstert.2014.04.023.
We provide a review of microRNA (miRNA) related to human implantation which shows the potential diagnostic role of miRNAs in impaired endometrial receptivity, altered embryo development, implantation failure after assisted reproduction technology, and in ectopic pregnancy and pregnancies of unknown location. MicroRNAs may be emerging diagnostic markers and potential therapeutic tools for understanding implantation disorders. However, further research is needed before miRNAs can be used in clinical practice for identifying and treating implantation failure.
我们提供了一篇关于与人类着床相关的 microRNA (miRNA) 的综述,该综述显示了 miRNA 在子宫内膜容受性受损、胚胎发育改变、辅助生殖技术后着床失败以及异位妊娠和不明位置妊娠中的潜在诊断作用。miRNA 可能成为诊断标志物和潜在治疗工具,有助于理解着床障碍。然而,在 miRNA 可用于临床识别和治疗着床失败之前,还需要进一步的研究。