Bhatt Vijaya Raj, Shrestha Rajesh, Shonka Nicole, Bociek R Gregory
Department of Internal Medicine, Division of Hematology-Oncology, University of Nebraska Medical Center, Omaha, NE, USA.
Department of Internal Medicine, Memorial Hospital of Rhode Island, Pawtucket, RI, USA.
J Clin Med Res. 2014 Aug;6(4):299-301. doi: 10.14740/jocmr1846w. Epub 2014 May 22.
Primary central nervous system (CNS) lymphoma, most frequently a diffuse large B-cell lymphoma, is a rare aggressive lymphoma confined to the CNS, thus requiring differentiation from other brain malignancies such as glioblastoma. Although stereotactic biopsy can confirm the diagnosis, this is invasive, not always feasible and can be inconclusive after steroid use. Hence, cranial magnetic resonance imaging (MRI) with contrast and cerebrospinal fluid analysis are frequently used to make a prompt diagnosis. We report a case of a woman with two brain masses who presented unique diagnostic challenge.
原发性中枢神经系统（CNS）淋巴瘤，最常见的是弥漫性大B细胞淋巴瘤，是一种局限于中枢神经系统的罕见侵袭性淋巴瘤，因此需要与其他脑恶性肿瘤如胶质母细胞瘤相鉴别。尽管立体定向活检可以确诊，但这是一种侵入性操作，并非总是可行，而且在使用类固醇后可能无法得出明确结论。因此，增强头颅磁共振成像（MRI）和脑脊液分析常用于快速做出诊断。我们报告一例患有两个脑肿块的女性病例，该病例带来了独特的诊断挑战。
