Hedstrom O, Sonn R, Dearing P, Snyder S P, Lassen E D
Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Oregon State University, Corvallis 97331-4802.
J Vet Diagn Invest. 1989 Apr;1(2):128-31. doi: 10.1177/104063878900100207.
The Veterinary Diagnostic Laboratory at Oregon State University received 172 aborted ovine fetuses during the 1985-1987 lambing seasons; from 120 of these, body fluids were evaluated for IgG levels. Fifty-two (43%) of the fetal fluids had immunoglobulin G (IgG) levels greater than 15 mg/dl. Forty-five (87%) of the fluids with elevated IgG levels were confirmed or presumed toxoplasma or chlamydia abortions. A mean fetal fluid IgG concentration of 111.5 +/- 78 mg/dl was found for the 26 toxoplasma abortions; for the 19 chlamydia abortions, a mean IgG concentration of 109 +/- 91 mg/dl was found. Antibody titers equal to or greater than 1:40 against Toxoplasma gondii were detected in 23 fetal fluids. Fetal fluid IgG concentration less than 15 mg/dl was found to be associated with bacterial organisms (i.e., Campylobacter sp.) as the confirmed or presumed cause of abortion. These results suggest that measurement of fetal fluid IgG concentration is a useful, supportive diagnostic test in determining the cause of ovine abortion, and should be included as a routine laboratory procedure for ovine abortion diagnosis.
俄勒冈州立大学兽医诊断实验室在1985 - 1987年产羔季节接收了172例流产的绵羊胎儿；其中120例的体液被评估了免疫球蛋白G（IgG）水平。52例（43%）胎儿体液的免疫球蛋白G（IgG）水平高于15mg/dl。45例（87%）IgG水平升高的体液被确诊或推测为弓形虫或衣原体感染导致的流产。26例弓形虫感染导致流产的胎儿体液中，IgG平均浓度为111.5±78mg/dl；19例衣原体感染导致流产的胎儿体液中，IgG平均浓度为109±91mg/dl。在23例胎儿体液中检测到抗弓形虫抗体效价等于或大于1:40。胎儿体液IgG浓度低于15mg/dl被发现与细菌病原体（如弯曲杆菌属）有关，这些细菌被确诊或推测为流产的原因。这些结果表明，测量胎儿体液IgG浓度是确定绵羊流产原因的一项有用的辅助诊断测试，应作为绵羊流产诊断的常规实验室程序。
