Bloch-Michel E
Bull Soc Belge Ophtalmol. 1989;230:53-8.
The clinical aspect of congenital toxoplasmosis is sometimes typical, sometimes atypical. The advantage of the serological study of the aqueous is an early diagnosis and an early treatment for less expense. The classical treatment relies on the therapeutic association Pyrimethamine + Adiazine + corticosteroids which will be used during acute phases, at ordinary doses, but may be prolonged further over many months in difficult cases. Severe forms are those that are spontaneously severe or increased with the exclusive use of corticosteroids in previous attacks, noticeably when injected by local route, and in bilateral forms. Prevention of ocular toxoplasmosis is represented by the detection of sero-conversion in mother and treatment in the newborn. Due to the legal aspect of this procedure in France, the incidence of congenital toxoplasmosis has already decreased during the past years and will continue to diminish in the next future. However the possibility of acquired forms cannot be excluded, even in non immuno-depressed patients.
先天性弓形虫病的临床症状有时典型，有时不典型。房水血清学研究的优势在于能够早期诊断并以较低费用进行早期治疗。传统治疗依赖于乙胺嘧啶+磺胺嘧啶+皮质类固醇的联合治疗，在急性期使用常规剂量，但在困难病例中可能需要延长数月。严重形式包括自发严重的情况，或在先前发作时仅使用皮质类固醇（尤其是局部注射时）病情加重的情况，以及双侧形式。眼部弓形虫病的预防表现为检测母亲的血清转化并对新生儿进行治疗。由于法国这一程序的法律层面，先天性弓形虫病的发病率在过去几年中已经下降，并且在未来还将继续降低。然而，即使在非免疫抑制患者中，也不能排除获得性感染的可能性。
