Tao Yungan, Vintonenko Nadejeda, Garcia Robin, Marchesi Vincent, Tomsej Milan, Bardet Etienne, Bourhis Jean
Institut Gustave Roussy, département de radiothérapie, 114 rue Edouard-Vaillant, 94800 Villejuif, France, Groupe d'oncologie radiothérapie tête et cou (GORTEC), Tours, France.
Groupe d'oncologie radiothérapie tête et cou (GORTEC), Tours, France.
Bull Cancer. 2014 May 1;101(5):481-5. doi: 10.1684/bdc.2014.1924.
The aim of radiotherapy is to deliver enough radiation to the tumor in order to achieve maximum tumour control in the irradiated volume with as few serious complications as possible with an irradiation dose as low as possible to normal tissue. The quality of radiotherapy is essential for optimal treatment and quality control is to reduce the bias in clinical trials avoiding possible major deviations. The assurance and quality control programs have been developed in large european (EORTC, GORTEC) and american cooperative groups (RTOG) of radiation oncology since the 1980s. We insist here on the importance of quality assurance in radiotherapy and the current status in this domain and the criteria for quality control especially for current clinical trials within GORTEC are discussed here.
放射治疗的目的是向肿瘤提供足够的辐射,以便在照射体积内实现最大程度的肿瘤控制,同时尽可能减少严重并发症,并将对正常组织的照射剂量降至最低。放射治疗的质量对于优化治疗至关重要,而质量控制是为了减少临床试验中的偏差,避免可能出现的重大偏差。自20世纪80年代以来,欧洲大型放射肿瘤学合作组织(欧洲癌症研究与治疗组织、法国放射肿瘤学和胃肠道肿瘤学研究组)和美国合作组织(放射肿瘤学治疗研究组)已经制定了保证和质量控制计划。在此,我们强调放射治疗中质量保证的重要性、该领域的现状,并讨论质量控制标准,特别是法国放射肿瘤学和胃肠道肿瘤学研究组内当前临床试验的质量控制标准。