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儿童散发性沙门氏菌病的相关危险因素:2008 - 2011年德国下萨克森州的一项病例对照研究

Risk factors associated with sporadic salmonellosis in children: a case-control study in Lower Saxony, Germany, 2008-2011.

作者信息

Ziehm D, Rettenbacher-Riefler S, Kreienbrock L, Campe A, Pulz M, Dreesman J

机构信息

Governmental Institute of Public Health of Lower Saxony,Hannover,Germany.

Department of Biometry, Epidemiology and Information Processing, WHO Collaboration Centre of Research and Training in Veterinary Public Health,University for Veterinary Medicine Hannover,Hannover,Germany.

出版信息

Epidemiol Infect. 2015 Mar;143(4):687-94. doi: 10.1017/S095026881400140X. Epub 2014 Jun 2.

Abstract

We conducted a case-control study based on 884 laboratory-confirmed sporadic Salmonella cases reported to the German infectious disease notification system. For controls, we recruited 510 rotavirus cases via the same system. Univariable and multivariable logistic regression analyses were performed separately for children aged 0-3 years and 4-14 years. In both age groups, the highest odds ratios (OR) were found for raw ground pork consumption [0-3 years: OR 8·6, 95% confidence interval (CI) 2·4-30·8; 4-14 years: OR 4·5, 95% CI 1·1-19]. Further risk factors were exposure to animals (OR 1·6, 95% CI 1·1-2·1), consumption of poultry (OR 1·5, 95% CI 1·1-2·1), food items containing eggs (OR 1·5, 95% CI 1·1-2) and black pepper (OR 1·7, 95% CI 1·1-3·5) in children aged 0-3 years, and consumption of uncooked pork sausage (OR 3·6, 95% CI 1·4-9·3) in children aged 4-14 years. This study highlights the significance of raw pork products ('Mett' in German) as risk factors for sporadic salmonellosis in children in Germany.

摘要

我们基于向德国传染病通报系统报告的884例实验室确诊的散发性沙门氏菌病例开展了一项病例对照研究。对于对照,我们通过同一系统招募了510例轮状病毒病例。分别对0至3岁和4至14岁的儿童进行了单变量和多变量逻辑回归分析。在这两个年龄组中,食用生绞碎猪肉的比值比(OR)最高[0至3岁:OR 8.6,95%置信区间(CI)2.4至30.8;4至14岁:OR 4.5,95% CI 1.1至19]。其他风险因素包括0至3岁儿童接触动物(OR 1.6,95% CI 1.1至2.1)、食用家禽(OR 1.5,95% CI 1.1至2.1)、含鸡蛋食品(OR 1.5,95% CI 1.1至2)和黑胡椒(OR 1.7,95% CI 1.1至3.5),以及4至14岁儿童食用未煮熟的猪肉香肠(OR 3.6,95% CI 1.4至9.3)。本研究强调了生猪肉制品(德语为“Mett”)作为德国儿童散发性沙门氏菌病风险因素的重要性。

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