Mossanen Matthew, Gore John L
University of Washington School of Medicine of Washington School of Medicine, Department of Urology, Seattle, Washington, USA.
Curr Opin Urol. 2014 Sep;24(5):487-91. doi: 10.1097/MOU.0000000000000078.
Bladder cancer is a common, complex, and costly disease. Every year in the USA, bladder cancer is responsible for 70 ,000 diagnosed cases and over 15, 000 deaths. Once diagnosed, patients with nonmuscle invasive bladder cancer (NMIBC) are committed to a lifetime of invasive procedures and potential hospitalizations that result in substantial direct and indirect costs.
Bladder cancer is the most costly cancer among the elderly, estimated at nearly $4 billion per year, and has the highest cost of any cancer when categorized on a per patient basis. The direct economic cost of NMIBC is fueled by the need for lifelong cystoscopic examination and variations in treatment algorithms. This fiscal burden is further compounded by the indirect impact on psychological health and quality of life of patients and their families. Despite the development of new technologies, such as novel urinary biomarkers and innovative cystoscopic methods, no alternative to cystoscopic surveillance has been established.
The management of patients with NMIBC is responsible for a substantial financial burden with indirect costs that extend beyond quantifiable direct costs.
膀胱癌是一种常见、复杂且成本高昂的疾病。在美国,每年有7万例膀胱癌确诊病例,超过1.5万人死亡。一旦确诊,非肌层浸润性膀胱癌(NMIBC)患者需终生接受侵入性检查并可能住院,这会导致大量直接和间接费用。
膀胱癌是老年人中成本最高的癌症,估计每年近40亿美元,按每位患者计算,其成本在所有癌症中最高。NMIBC的直接经济成本因需要终生膀胱镜检查以及治疗方案的差异而增加。这种财政负担因对患者及其家人心理健康和生活质量的间接影响而进一步加重。尽管新技术不断发展,如新型尿液生物标志物和创新的膀胱镜检查方法,但尚未确立替代膀胱镜监测的方法。
NMIBC患者的管理会带来巨大的经济负担,其间接成本超出了可量化的直接成本。