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基于患者需求(包括吸烟和其他危险生活方式因素)的膀胱肿瘤经尿道切除术患者生活方式干预的潜力:一项横断面研究。

The Potential for Lifestyle Intervention Among Patients Undergoing Transurethral Resection of Bladder Tumour Based on Patient Needs Including Smoking and Other Risky Lifestyle Factors: A Cross-Sectional Study.

作者信息

Lydom Line Noes, Lauridsen Susanne Vahr, Joensen Ulla Nordström, Tønnesen Hanne

机构信息

WHO-CC/Clinical Health Promotion Centre, The Parker Institute, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, 2000 Frederiksberg, Denmark.

Centre for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, 2730 Herlev, Denmark.

出版信息

Int J Environ Res Public Health. 2024 Dec 8;21(12):1633. doi: 10.3390/ijerph21121633.

Abstract

Bladder cancer is the tenth most common cancer worldwide, with non-muscle invasive bladder cancer (NMIBC) accounting for 75% of cases. Transurethral resection of bladder tumours (TURBT) is the standard treatment, but it is associated with significant risks of complications and recurrence. Risky lifestyle factors, including smoking, malnutrition, obesity, risky alcohol use, and physical inactivity (collectively termed SNAP factors), may worsen surgical outcomes and increase cancer recurrence. Prehabilitation programmes targeting these modifiable risk factors could improve patient outcomes. This cross-sectional study assessed 100 TURBT patients at a Danish university hospital to determine the prevalence of SNAP factors and the potential for lifestyle interventions. Data were collected via structured interviews, and intervention scenarios were projected based on efficacy rates of 5-100%. In total, 58% of patients had at least one risky SNAP factor, with smoking (29%) being the most prevalent, followed by physical inactivity (19%) and risky alcohol use (18%). Obesity (7%) and malnutrition (8%) were less common. Seventeen percent had multiple SNAP factors. No significant demographic indicators were associated with the presence of SNAP factors. TURBT patients with NMIBC show a high prevalence of risky lifestyle factors, including smoking and obesity, with over half affected. Systematic screening and targeted interventions could significantly improve patient outcomes and long-term health.

摘要

膀胱癌是全球第十大常见癌症,其中非肌肉浸润性膀胱癌(NMIBC)占病例的75%。经尿道膀胱肿瘤切除术(TURBT)是标准治疗方法,但它与并发症和复发的重大风险相关。包括吸烟、营养不良、肥胖、危险饮酒和身体活动不足(统称为SNAP因素)在内的不良生活方式因素可能会使手术结果恶化并增加癌症复发风险。针对这些可改变风险因素的术前康复计划可能会改善患者预后。这项横断面研究评估了丹麦一家大学医院的100名接受TURBT手术的患者,以确定SNAP因素的患病率以及生活方式干预的可能性。通过结构化访谈收集数据,并根据5%-100%的有效率预测干预方案。总体而言,58%的患者至少有一个危险的SNAP因素,其中吸烟(29%)最为普遍,其次是身体活动不足(19%)和危险饮酒(18%)。肥胖(7%)和营养不良(8%)则不太常见。17%的患者有多个SNAP因素。没有显著的人口统计学指标与SNAP因素的存在相关。患有NMIBC的TURBT患者表现出包括吸烟和肥胖在内的不良生活方式因素的高患病率,超过半数患者受到影响。系统筛查和针对性干预可显著改善患者预后和长期健康状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d02/11675626/1a3e810eb05c/ijerph-21-01633-g001.jpg

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