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术后房颤的临床及超声心动图预测因素

Clinical and echocardiographic predicators of postoperative atrial fibrillation.

作者信息

Elawady Mohamed Ahmed, Bashandy Mohamed

机构信息

Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia Cardiothoracic Surgery Department, Banha Faculty of Medicine, Banha University, Egypt

Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia Cardiology Department, Faculty of Medicine, Alazhar University, Egypt.

出版信息

Asian Cardiovasc Thorac Ann. 2014 Jul;22(6):655-9. doi: 10.1177/0218492313503572. Epub 2013 Nov 5.

Abstract

BACKGROUND

Postoperative atrial fibrillation is the most common arrhythmia after coronary artery bypass grafting, with a reported incidence of 10% to 60%. Preoperative clinical and echocardiographic data, especially the atrial electromechanical interval, predict postoperative atrial fibrillation in elective coronary artery bypass patients.

METHODS

A prospective study evaluated preoperative clinical and echocardiographic data in 192 patients who underwent elective coronary artery bypass from 2010 to 2012.

RESULTS

18 (9.37%) patients developed postoperative atrial fibrillation. Compared to patients without postoperative atrial fibrillation, these 18 had significantly longer intensive care unit and hospital stays, they were significantly older (58.62 ± 10.02 vs. 53.22 ± 8.23 years; p = 0.02), with a larger left atrial volume (83.39 ± 8.31 vs. 55.47 ± 8.37 cm(3), p = 0.001), longer atrial electromechanical interval (133.67 ± 8.15 vs. 98.05 ± 6.71 ms p < 0.0001), and lower tissue Doppler imaging systolic velocity wave amplitude (6.6 ± 1 vs. 9.4 ± 2.2 cm·s(-1); p = 0.001); they also had a higher prevalence of hypertension (61.11% vs. 38.5%; p = 0.04). Using 115 ms as the cutoff value of atrial electromechanical interval enabled us to detect patients who developed postoperative atrial fibrillation with 100% sensitivity, 77% specificity, 78% positive predictive value, and 100% negative predictive value.

CONCLUSION

Older hypertensive patients are at higher risk of developing postoperative atrial fibrillation. Preoperative measurement of atrial electromechanical interval by tissue Doppler echocardiography is a useful predictor of postoperative atrial fibrillation in coronary artery bypass patients.

摘要

背景

术后房颤是冠状动脉搭桥术后最常见的心律失常,报道的发生率为10%至60%。术前临床和超声心动图数据,尤其是心房机电间期,可预测择期冠状动脉搭桥患者术后房颤的发生。

方法

一项前瞻性研究评估了2010年至2012年接受择期冠状动脉搭桥手术的192例患者的术前临床和超声心动图数据。

结果

18例(9.37%)患者发生术后房颤。与未发生术后房颤的患者相比,这18例患者的重症监护病房和住院时间明显更长,年龄明显更大(58.62±10.02岁对53.22±8.23岁;p = 0.02),左心房容积更大(83.39±8.31对55.47±8.37 cm³,p = 0.001),心房机电间期更长(133.67±8.15对98.05±6.71 ms,p < 0.0001),组织多普勒成像收缩期速度波幅度更低(6.6±1对9.4±2.2 cm·s⁻¹;p = 0.001);他们患高血压的患病率也更高(61.11%对38.5%;p = 0.04)。以115 ms作为心房机电间期的截断值,能够100%敏感地检测出发生术后房颤的患者,特异性为77%,阳性预测值为78%,阴性预测值为100%。

结论

老年高血压患者发生术后房颤的风险更高。术前通过组织多普勒超声心动图测量心房机电间期是冠状动脉搭桥患者术后房颤的有用预测指标。

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