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法洛四联症初次修复术:重症监护病房发病的预测因素

Primary tetralogy of Fallot repair: predictors of intensive care unit morbidity.

作者信息

Egbe Alexander C, Uppu Santosh C, Mittnacht Alexander J C, Joashi Umesh, Ho Deborah, Nguyen Khanh, Srivastava Shubhika

机构信息

Division of Pediatric Cardiology, Mount Sinai Hospital, New York, USA

Division of Pediatric Cardiology, Mount Sinai Hospital, New York, USA.

出版信息

Asian Cardiovasc Thorac Ann. 2014 Sep;22(7):794-9. doi: 10.1177/0218492313513773. Epub 2013 Nov 22.

Abstract

BACKGROUND

Primary repair of tetralogy of Fallot has low surgical mortality, but some patients still experience significant postoperative morbidity. Our objectives were to review our institutional experience with primary tetralogy of Fallot repair, and identify predictors of intensive care unit morbidity.

METHODS

We reviewed all patients with tetralogy of Fallot who underwent primary repair in infancy from 2001 to 2012. Preoperative, operative, and postoperative demographic and morphologic data were analyzed. Intensive care unit morbidity was defined as prolonged intensive care unit stay (≥ 7 days) and/or prolonged duration of mechanical ventilation (≥ 48 h).

RESULTS

97 patients who underwent primary surgical repair during the study period were included in the study. The median age was 4.9 months (range 1-9 months) and the median weight was 5.3 kg (range 3.1-9.8 kg). There was no early surgical mortality. The incidence of junctional ectopic tachycardia and persistent complete heart block was 2% and 1%, respectively. The median intensive care unit stay was 6 days (range 2-21 days) and the median duration of mechanical ventilation was 19 h (range 0-136 h). Age and weight were independent predictors of intensive care unit stay, while surgical era predicted the duration of mechanical ventilation.

CONCLUSION

Primary tetralogy of Fallot repair is a safe procedure with low mortality and morbidity in a medium-sized program with outcomes comparable to national standards. Age and weight at the time of surgery were significant predictors of morbidity.

摘要

背景

法洛四联症的一期修复手术死亡率较低,但部分患者术后仍有明显的并发症。我们的目的是回顾我院法洛四联症一期修复手术的经验,并确定重症监护病房并发症的预测因素。

方法

我们回顾了2001年至2012年期间所有在婴儿期接受一期修复手术的法洛四联症患者。分析术前、术中及术后的人口统计学和形态学数据。重症监护病房并发症定义为重症监护病房住院时间延长(≥7天)和/或机械通气时间延长(≥48小时)。

结果

本研究纳入了研究期间接受一期手术修复的97例患者。中位年龄为4.9个月(范围1 - 9个月),中位体重为5.3千克(范围3.1 - 9.8千克)。无早期手术死亡病例。交界性异位性心动过速和持续性完全性心脏传导阻滞的发生率分别为2%和1%。重症监护病房中位住院时间为6天(范围2 - 21天),机械通气中位时间为19小时(范围0 - 136小时)。年龄和体重是重症监护病房住院时间的独立预测因素,而手术时代是机械通气时间的预测因素。

结论

在一个中等规模的项目中,法洛四联症一期修复手术是一种安全的手术,死亡率和并发症发生率较低,其结果与国家标准相当。手术时的年龄和体重是并发症的重要预测因素。

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