Mangiarotti P, Manara G, Bianchi L, Piccioni P D, Grassi C
G Ital Chemioter. 1989 Jan-Dec;36(1-3):89-94.
A clinical trial was performed to evaluate the efficacy of ciprofloxacin by iv administration in the treatment of respiratory infections. Twenty-two in-patients affected with acute lower respiratory tract infections, mainly infectious exacerbations of chronic obstructive lung disease (COLD), were treated with ciprofloxacin at the daily dosage of 400 mg iv, in two administrations. Overall clinical results were satisfactory (15 patients cured, 7 patients improved). Concerning bacteriological results, pathogen eradication was achieved in 83.3% of cases. Tolerability was good: no adverse events were observed.
进行了一项临床试验,以评估静脉注射环丙沙星治疗呼吸道感染的疗效。22名患有急性下呼吸道感染(主要是慢性阻塞性肺病(COLD)的感染性加重)的住院患者接受了静脉注射环丙沙星治疗,每日剂量为400毫克,分两次给药。总体临床结果令人满意(15例治愈,7例好转)。关于细菌学结果,83.3%的病例实现了病原体根除。耐受性良好:未观察到不良事件。