Pastushenko I, Conejero C, Carapeto F J
Servicio de Dermatología, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España.
Servicio de Dermatología, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España.
Actas Dermosifiliogr. 2015 Jan-Feb;106(1):7-16. doi: 10.1016/j.ad.2014.02.013. Epub 2014 Jun 2.
Disease course in melanoma often cannot be accurately predicted by means of the prognostic factors usually considered in patients with melanoma; therefore, new factors are clearly needed. Increasingly robust scientific evidence shows that tumor lymph vessels play a key role in melanoma that metastasizes by lymphatic and hematogenous pathways. We review current knowledge and examine the implications of lymphangiogenesis in the diagnosis, treatment, and prognosis of patients with melanoma.
黑色素瘤的病程通常无法通过黑色素瘤患者通常所考虑的预后因素准确预测；因此，显然需要新的因素。越来越有力的科学证据表明，肿瘤淋巴管在通过淋巴和血行途径转移的黑色素瘤中起关键作用。我们回顾了当前的知识，并探讨了淋巴管生成在黑色素瘤患者诊断、治疗及预后方面的意义。
